Neonorm™ Calf is our non-prescription product to help dairies and calf farms proactively retain fluid in calves—helping the animals avoid debilitating, dangerous levels of dehydration (learn more).
Neonorm Calf is an enteric-coated bolus designed to be given orally to preweaned dairy calves once every 12 hours, as needed, for up to three days. Neonorm Calf was the subject of a study published in the official journal of the American Dairy Science Association, Journal of Dairy Science—a leading peer-reviewed general dairy research journal, in 2015. The study, which was conducted by researchers from Cornell University College of Veterinary Medicine, suggests that Neonorm Calf can significantly increase the fecal dry matter of neonatal calves with experimentally-induced enterotoxigenic E. coli diarrhea.
Higher fecal dry matter is an indication of less water loss and lower dehydration risk in the calf. In addition, the study also displayed a beneficial effect of the Neonorm botanical extract in supporting weight gain in calves at 10 days of life. Weight gain during the preweaning period influences the lifetime productivity of dairy cattle, impacting mammary gland development, the timing of puberty, and the age at which dairy cows first produce milk.
Equine Formulations of Neonorm
Often, diarrhea occurs in the first 30 days of the foal’s life, both from infections and non-infectious causes, such as lactose intolerance and overfeeding. Some cases are severe and life threatening. A majority of foals will exhibit diarrhea at some point within the first two months of life. Episodic diarrhea is mostly associated with diseases of the large intestine and damage to the colon or disturbance of colonic function. Typically, diarrhea in horses is treated with fluid replenishment and electrolytes, deworming agents and antibiotics, and intestinal protectants and absorbents, as well as anti-motility agents. There are no anti-secretory products approved by the FDA for veterinary use.
Neonorm For Other Production Animals
We believe that due to Neonorm’s mechanism of action and our data in preweaned dairy calves, we will be able to develop and commercialize species-specific formulations of Neonorm for beef cattle and multiple other animal species, such as horses, goats and sheep. In less developed nations, where not only dairy and beef cattle but also buffalo, goat and sheep provide livelihoods for local populations, reducing losses related to diarrhea can provide significant monetary, social and health benefits.